GUY, Isabel (Wilkie) Of Lexington, March 19, 2012. Beloved wife of Matthew C. Guy for 56 years. Mother of Sandra Cox and her husband Alan of Merrimac, Stephen B. Guy and his wife Kathleen of Woburn, Dr. Matthew C. Guy, Jr. and his wife Yvonne of Billerica, and Robert A. Guy of Woburn. She is survived by her two sisters, Jean and Muriel, and predeceased by her sister Margaret of Dundee, Scotland. Isabel is also survived by her grandchildren, Melissa, Elizabeth, Grant, Duncan and Matthew, along with many nieces and nephews. Isabel emigrated from Scotland at the age of 20 to Massachusetts where she became a registered nurse, married and raised a family. Visiting hours will be held Sunday, March 25 at the Douglass Funeral Home, 51 Worthen Rd., LEXINGTON, from 5pm to 8pm and a funeral service at Grace Chapel, 59 Worthen Rd. Lexington on Monday March 26 at 11am. Relatives and friends are kindly invited to attend. Donations in her memory may be made to The Home for Little Wanderers, 271 Huntington Ave. #2 Boston, MA 02115 or to Horizons for Homeless Children, Attn. Katie Corradini, 1705 Columbus Ave. Roxbury, MA 02119. Private interment Woodlawn Cemetery, Everett.